Hey everyone!! Welcome back to my blog! Today we will be continuing the topic glycolysis by focusing on phase two of glycolysis which is known as the Energy Generation Phase. Happy Learning!
Reaction 6
· Enzyme- Triose phosphate dehydrogenase
· Enzyme transfers a hydrogen from glyceraldehydes-3-phosphate to NAD+ and NADH forms
· Enzyme also adds a phosphate to the glyceraldehydes-3-phosphate to form 1,3-bisphosphoglycerate
Reaction 7
· Enzyme- Phosphoglycerokinase
· For each 1,3-bisphosphoglycerate the enzyme transfers a phosphate to a molecule of ADP to form ATP
· Two 3-phosphoglycerate molecules and 2 ATP molecules are formed
Reaction 8
· Enzyme- Phosphoglyceromutase
· The enzyme moves the phosphate from 3-phosphoglycerate on the 3rd carbon to the 2nd carbon to form 2-phosphoglycerate
Reaction 9
· Enzyme- Enolase
· The enzyme removes a molecule of water from 2-phosphoglycerate to form phosphoenolpyruvate
· Dehydration reaction
Reaction 1o
· Enzyme- Pyruvate kinase
· The enzyme transfers a phosphate from PEP to form pyruvate and ATP
· The second ATP molecule is formed by substrate level phosphorylation
Overall: A single glucose molecule in glycolysis produces a total of 2 molecules of pyruvate, 2 molecules of ATP, 2 molecules of NADH & 2 molecules of water.See image below. Click on image for larger version.
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References
Featured Image: http://www.uic.edu/classes/bios/bios100/lectf03am/lect11.htm
Youtube: BiochemJM
Image:
http://www.sparknotes.com/biology/cellrespiration/glycolysis/problems.html#explanation1